Can acute GVHD that appeared on day 70 recur or worsen in severity later?
Yes, acute GVHD that appeared on day 70 can recur or worsen later. There are a few ways this can happen:
Acute GVHD can take three different forms after initial onset:
* Persistent GVHD - Symptoms continue past day 100 without improvement
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Can acute GVHD that appeared on day 70 recur or worsen in severity later?
Yes, acute GVHD that appeared on day 70 can recur or worsen later. There are a few ways this can happen:
Acute GVHD can take three different forms after initial onset:
* Persistent GVHD - Symptoms continue past day 100 without improvement
* Recurrent GVHD - The condition gets better for a while but then comes back
* Late-onset acute GVHD - Symptoms return when immunosuppressant medications are stopped or reduced
The severity can also change over time. If you don't respond well to steroid treatment (called steroid-refractory GVHD), your symptoms may worsen and require second-line treatments.
It's important to stay in close contact with your transplant team and report any new or worsening symptoms right away. This helps them adjust your treatment as needed. Always follow your treatment plan and consult your doctor before making any changes to your medications, as stopping immunosuppressants can trigger symptoms to return.
November 17