I think GVHD has returned after 15+ years

A myGVHDteam Subscriber asked a question 💭

I received a BMT from an unrelated donor in 2009 to treat MDS that progressed into AML. Since late may I have had several unsettling symptoms develop. I’ve lost a good amount of weight without trying - in dec of 2025 I was 146 lbs, as of today I am down to 116. I have had body aches, night sweats, dry mouth, on and off chest pain, a few mouth sores, spots of singular petechiae and a few instances of random clusters & extreme fatigue. I went to the er around Father’s Day for a dizzy spell and they gave me a CT with contrast - I ended up having a delayed full body cutenous reaction to the contrast 2/3 days after my visit. It was odd because I have had many many scans with the dye and have never had problems. I went back to the er to treat the rash and was administered prednisone and sent home with a 4 day supply - while taking that med I noticed not only the rash going away but all of my other symptoms completely improved. Within a week of finishing my last dose symptoms started returning.
I was treated for pretty severe acute GVHD very shortly after my transplant in 2009/2010 and recall taking prednisone/cyclosporine for at least a year or 2.

My abdominal CT revealed mild hydronephrosis with both kidneys. And bloodwork showed elevated abso monocytes. Other then that the tests ran in the er were fairly normal looking.

July 23
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