myGVHDteam

Graft-versus-host disease (GVHD) is a complication that can occur after an allogeneic stem cell transplant (also called a bone marrow transplant), where donor cells are used. In this situation, the donated immune cells — the "graft" — mistakenly identify the recipient's healthy cells as foreign invaders and begin to attack Show Full Answer

Graft-versus-host disease (GVHD) is a complication that can occur after an allogeneic stem cell transplant (also called a bone marrow transplant), where donor cells are used. In this situation, the donated immune cells — the "graft" — mistakenly identify the recipient's healthy cells as foreign invaders and begin to attack them, causing damage to tissues and organs. There are two main types of GVHD:

- Acute GVHD – Comes on suddenly, typically within the first 100 days after a transplant, though it can appear up to six months later
- Chronic GVHD – Develops more slowly and can last a long time, usually appearing 100 days or more after a transplant
- Overlap syndrome – When both acute and chronic GVHD occur at the same time

Symptoms can range from mild to life-threatening, depending on which organs are affected and how severe the condition is. Early diagnosis and treatment are really important for the best possible outcome.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Overview of Graft-Versus-Host Disease: 9 Facts To Know

4 Types of Graft-Versus-Host Disease: Acute, Chronic, Overlap, and Late Acute