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July 12, 2025
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GVHD (Graft-Versus-Host Disease) is a condition that can affect multiple organs in the body following a transplant. It can be acute or chronic, and in some cases may become life-threatening. While doctors previously classified GVHD based on timing after transplant, current guidelines focus more on the type and severity of Show Full Answer

GVHD (Graft-Versus-Host Disease) is a condition that can affect multiple organs in the body following a transplant. It can be acute or chronic, and in some cases may become life-threatening. While doctors previously classified GVHD based on timing after transplant, current guidelines focus more on the type and severity of symptoms. Common symptoms of GVHD include:

• Skin issues - rashes, color changes, blistering
• Eye problems - dryness, irritation
• Mouth symptoms - sores, ulcers
• Liver problems - jaundice
• Gastrointestinal issues - diarrhea, abdominal pain
• Lung problems - shortness of breath, dry cough
• Joint/muscle symptoms - pain, swelling, stiffness
• Genital area changes - discomfort, changes in function

The severity can range from mild to severe depending on how many organs are affected and the intensity of symptoms.

July 12, 2025
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